If you want to go “all in” on crazy you can start looking at motorized dampers or vent misers (failed product of the mid 2000s?) and make a DIY zoning setup. I started my trek down this path about a year and a half ago when we had our twins. I thought it was ludicrous to heat/cool the entire house just to keep the nursery warm ( i was used to keeping the heat off at night even with the house dipping into the 50s way into the night - on extremely cold nights). At first I had an oil filled radiator for their room but I think it cost as much to run that for their room as it did to heat the house.
So, remembering seeing motorized vents by a company called Keen I thought about doing that. But, at 80 dollars a vent (i think) I couldn’t swallow it. I had just just dipped my toe into the arduino pool about this time and I thought maybe I could use a servo to open and close a regular vent. Well into researching that and how to make it all work I found vent misers. My prayer was answered. Motorized vents for like…10 bucks a piece on ebay. All i had to do was get an arduino to open and close them on demand.
18 Months later and now most rooms have their own temperature sensors, setpoints, and motorized vent to regulate temperature. Another arduino (esp8266) controls an 8-relay board that calls for heat/cool (including cutting the hi heat stage) and selects a different fan speed on the furnace based on how many vents are open.
The house can be 80 degrees while the nursery and master are a cool 74 at night. So…there are options for you