The locking issue is the problem—see the long thread (bottom of it) for more on that, as well as a good few reports on Github. There is an underlying issue in either nrjavaserial or in OH itself that affects lock handling with USB devices. The only way I have managed to bypass that is by using rfc2217 connection to a remote Pi running nothing other than the ZWave stick (and RFXCOM USB in my case).
Any other issues? I am not sure if Homekit integration works and I do not know if that is a FreeBSD or an OH issue. I have just failed on it, and I am awaiting info on a newer jar of the add-on to test. Having hit a good few walls with OH on FreeBSD so far, I am experimenting with HA+FreeBSD which seems to run smoother, no locking issues etc. 