I started with RaspberryPi 3 and RaZberry (the first gen). I remember struggling with serialPorts, needed to pass environment variables to the karaf, disable on-board Bluetooth… Lots of hassle. See issue on openHABian github for the reference.
Need to mention that it was before @pathec published his great Z-Way binding so right now is most probably less painful to configure 
Anyway I decided to set up my gear around Z-Stick S2 - so far no issues, works out of the box with the Z-Wave binding. I observed that the range improved as well.