Hi Russ @rpwong
Do you have anything in /etc/udev
related to the Zooz S2?
I am reading the thread: [SOLVED] OH3: zwave binding Z-Wave Serial Controller Aeotec Z-Stick Gen5 remains offline - #4 by hmerk recommended by @robmac
That thread indicates the stick in question has the file /etc/udev/99-usb-serial.rules
My install has nothing in udev . . .